Endocrine Abstracts

We report a 32-year-old primigravida with type 2 diabetes and large uterine fibroid who was found to have incidental, asymptomatic, non-PTH driven hypercalcaemia of 2.67 mmol/l (NR 2.2-2.60 mmol/l) at 7 weeks gestation. Investigations revealed no evidence of malignancy. Interestingly, following initial blood test, her calcium normalised but with persistent complete suppression of PTH until 19 weeks gestation, when her calcium rose to 3.25 mmol/l. Her 1,25-dihydroxy Vitamin D w...

Introduction: Cushing’s syndrome can impair the gonadotrophic axis in women of child bearing age if left untreated. Furthermore undergoing endoscopic transphenoidal surgery can render patients hypogonadal, thereby reducing the chances of spontaneous conception. In such cases, pregnancy is usually achieved by assisted contraceptive techniques. We present a case of spontaneous pregnancy following transphenoidal surgery and bilateral adrenalectomy.Case...

Introduction: Hyponatraemia is a common electrolyte abnormality seen among hospitalised patients. We describe below, an inpatient seen with severe hyponatraemia.Case description: 71yr old gentleman with no co-morbidities, admitted with acute confusion and slurred speech. Physical examination: Observations: Temperature 35C, heart rate 53/min, otherwise stable. GCS 15/15, no focal neurolo...

Introduction: Vitamin D (Vit D) is required for maintaining optimal bone health and there is widespread campaign in the media for its use. There is however lack of awareness among the general public about therapeutic doses which if exceeded can result in harm. We present one such patient who was taking harmful quantities of vit D supplements procured over the internet which resulted in hypercalcaemia and renal failure.Case Description: 50year old lady, N...